Deep Vein Thrombosis Associated with Marked Hyperhomocysteinemia and Active Pulmonary Tuberculosis
نویسندگان
چکیده
We report a 32-year-old male patient presented with acute deep vein thrombosis of his right leg after recent onset of active pulmonary tuberculosis. Marked hyperhomocysteinemia (> 50 umol/L), folic acid deficiency, and abnormal coagulation profiles (elevations of fibrinogen and fibrinogen degradation product) were noted after a series of work-ups. After treatment with low-molecular-weight heparin, deep vein thrombosis improved. Serum homocysteine level returned to normal after folic acid and vitamin B12 supplementation for 2 months. After therapy with fourcombined anti-tuberculosis drugs for 9 months, the pulmonary tuberculosis subsided. In the present case report, the cause of hyperhomocysteinemia may be related to folic acid deficiency and chronic renal insufficiency.
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